Document Detail


Microembolic signals in subarachnoid hemorrhage.
MedLine Citation:
PMID:  19138849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Microembolic signals (MES) detected by transcranial Doppler (TCD) have been reported in subarachnoid hemorrhage (SAH), although their origin and contribution to brain ischemia remain uncertain. We conducted a prospective study to evaluate the frequency of MES among patients with SAH and to determine their origin. Twenty-seven patients with SAH, comprising 15 aneurysmal and 12 non-aneurysmal patients, participated in the study. TCD evaluation was performed using a 2 MHz probe. Patients were studied three times per week during their in-patient stay to detect vasospasm, and then each middle cerebral artery (MCA) was monitored for 30 min using the Monolateral Multigate mode to detect MES. Using this method, MES were detected in 7 out of 15 patients (47%) with aneurysmal SAH and were not seen in non-aneurysmal patients (p=0.007). Vasospasm occurred in 52% (14/27) of cases. However, clinical signs and symptoms of vasospasm were identified in only 18.5% (5/27). There was no significant relationship between MES and vasospasm (p=0.224). Also, no relationship was found between MES and the location of the aneurysm (p=0.685). Thus, in this study MES were only detected in aneurysmal SAH. However, we did not find a relationship between the location of the aneurysm and MES, or the presence of vasospasm and MES. Therefore, MES in patients with SAH may also originate from vascular pathology other than the aneurysm sac or vascular spasm.
Authors:
Mahmoud Reza Azarpazhooh; Arash Velayati; Brian R Chambers; Hossain Mashhadi Nejad; Payam Sasan Nejad
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-12
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  16     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-10     Completed Date:  2009-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  390-3     Citation Subset:  IM    
Affiliation:
Department of Neurology, Ghaem Medical Center, Mashhad University of Medical Science (MUMS), Taghi Abad Square, Mashhad 9196773117, Iran. azarpazhoohmr@mums.ac.ir
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Chi-Square Distribution
Female
Humans
Intracranial Aneurysm / complications,  ultrasonography
Intracranial Embolism / etiology*,  ultrasonography
Male
Middle Aged
Retrospective Studies
Subarachnoid Hemorrhage / complications*,  ultrasonography
Ultrasonography, Doppler, Transcranial / methods
Vasospasm, Intracranial / diagnosis
Young Adult

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