Document Detail

Microemboli in aneurysmal subarachnoid hemorrhage.
MedLine Citation:
PMID:  18494776     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: The determinants of ischemic complications in subarachnoid hemorrhage (SAH) are not well defined. The objective of this study is to evaluate the role of microemboli in SAH-related cerebral ischemia. METHODS: Forty patients with aneurysmal SAH were monitored with transcranial Doppler (TCD) for the presence of embolic signals (ES) and vasospasm, and followed clinically for the development of cerebral ischemic symptoms, from the time the aneurysm was secured until day 14 posthemorrhage or discharge. RESULTS: Microembolic signals were detected in 15/40 patients, appeared at a mean of 6.7 days after hemorrhage, and were often noted bilaterally. There was a close association between ES and cerebral ischemic symptoms (P= .003), and ES were commonly present in the distribution of the vessel with ischemic symptoms. Ultrasonographic vasospasm did not correlate with ischemia and there was no relationship between microembolic signals and vasospasm. CONCLUSIONS: In this study, ES detected in over a third of SAH victims, were associated with the development of cerebral ischemic symptoms, and were not related to vasospasm, but rather appeared to be an independent risk factor for the development of ischemic symptoms in SAH.
Jose G Romano; Alejandro A Rabinstein; Kristopher L Arheart; Sandra Nathan; Iszet Campo-Bustillo; Sebastian Koch; Alejandro M Forteza
Related Documents :
20665216 - Pulmonary hemorrhage complicating radiofrequency ablation, from mild hemoptysis to life...
22166766 - Coarctation of the aorta and vein of galen malformation - treatment considerations in a...
11493366 - Treatment of aneurysmal subarachnoid haemorrhage in elderly patients.
9664756 - Multiple intracerebral hemorrhages and vasospasm following antimigrainous drug abuse.
19797226 - Oscillation of angiogenesis with vascular dropout in diabetic retinopathy by vessel gen...
2485906 - Comparative in vitro study of rgh-2981, a new peripheral blood flow enhancer on animal ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-05-19
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  18     ISSN:  1552-6569     ISO Abbreviation:  J Neuroimaging     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-11-17     Completed Date:  2009-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  396-401     Citation Subset:  IM    
Department of Neurology, University of Miami, Miami, FL, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aneurysm, Ruptured / therapy,  ultrasonography*
Brain Ischemia / therapy,  ultrasonography
Embolization, Therapeutic
Follow-Up Studies
Glasgow Outcome Scale
Image Processing, Computer-Assisted*
Intracranial Aneurysm / therapy,  ultrasonography*
Intracranial Embolism / therapy,  ultrasonography*
Middle Aged
Sensitivity and Specificity
Subarachnoid Hemorrhage / therapy,  ultrasonography*
Surgical Instruments
Ultrasonography, Doppler, Transcranial*
Vasospasm, Intracranial / therapy,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Systemic thrombolysis based on CT or MRI stroke imaging.
Next Document:  Various origins of the duplicated middle cerebral artery.