Document Detail

Microdermabrasion: a clinical and histopathologic study.
MedLine Citation:
PMID:  11442587     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Microdermabrasion is a widely performed skin rejuvenation procedure. Few studies have examined its efficacy. OBJECTIVE: To evaluate the clinical and histopathologic effects of microdermabrasion. METHODS: Fourteen patients underwent microdermabrasion treatments over 12-14 weeks. Self-rated questionnaires were given before and after the treatment series and were evaluated by a paired t-test. Three of the 14 patients were treated for moderate to severe acne scarring. Acute histologic effects were assessed ex vivo on human abdominal skin. Chronic histopathologic effects were examined in three volunteers who underwent skin biopsies before and after a treatment series on the dorsal forearms. RESULTS: By patient assessment, there was statistically significant improvement in roughness, mottled pigmentation, and overall improvement of skin appearance, but not in rhytides. Acne scarring sometimes improved, but required deeper ablation. Acutely the stratum corneum was homogenized and focally compacted. Chronically there was epidermal hyperplasia, decreased melanization, and some increase in elastin. CONCLUSION: Microdermabrasion improves some aspects of photoaging and select cases of acne scarring.
E K Shim; D Barnette; K Hughes; H T Greenway
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  27     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-07-09     Completed Date:  2001-07-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  524-30     Citation Subset:  IM    
Division of Dermatology and Cutaneous Surgery, Scripps Clinic and Research Foundation, La Jolla, CA, USA.
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MeSH Terms
Acne Vulgaris / pathology,  surgery*
Middle Aged
Skin / pathology*,  surgery*
Skin Aging / pathology*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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