Document Detail

Microcytotoxicity and serum blocking factors in malignant melanoma and halo nevus.
MedLine Citation:
PMID:  1094959     Owner:  NLM     Status:  MEDLINE    
Microcytotoxicity assays of patients with malignant melanoma and halo nevi were performed. No good correlation could be found between percent cell inhibition and histopathological level of melanoma or the clinical staging. The percent cell inhibition was usually an index of response to vaccinia virus immunotherapy. Actively regressing halo nevi showed high levels of percent cell inhibition, whereas inactive halo nevi had low levels of percent cell inhibition and blocking factor. Immunologic reactivity to melanoma cells may be a common feature of melanoma and halo nevus.
H H Roenigk; S D Deodhar; J A Krebs; B Barna
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Publication Detail:
Type:  In Vitro; Journal Article; Review    
Journal Detail:
Title:  Archives of dermatology     Volume:  111     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-09-05     Completed Date:  1975-09-05     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  720-5     Citation Subset:  AIM; IM    
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MeSH Terms
BCG Vaccine
Culture Techniques
Cytotoxicity Tests, Immunologic
Fluorescent Antibody Technique
Melanoma / immunology*,  pathology
Mycobacterium bovis
Nevus / immunology*,  pathology
Vaccinia virus / immunology
Reg. No./Substance:
0/BCG Vaccine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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