Document Detail


Microcystic adnexal carcinoma: report of four cases treated with Mohs' micrographic surgical technique.
MedLine Citation:
PMID:  15941444     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Microcystic adnexal carcinoma (MAC) is a rare and aggressive malignant tumor of the sweat glands. Clinically, it often presents as a firm subcutaneous nodule on the head and neck regions. On histology, MAC exhibits both pilar and sweat duct differentiation with a stroma of dense collagen. It often extends beyond the clinical margins with local spreading in the dermal, subcutaneous, and perineural tissue planes. It has a high local recurrence rate after standard excision. Recent preliminary reports have indicated more favorable cure rates with Mohs' micrographic surgery (MMS). OBJECTIVE: To present our data on four cases of MAC treated by MMS. We also compared our findings with more recently reported series in the English language literature. METHODS: We reviewed the medical records of four patients (two males and two females) with MAC treated by MMS over the last 3 years. We also obtained follow-up data. RESULTS: In all four patients with MAC treated by MMS, there were no recurrences, with a mean follow-up of 1 year. CONCLUSION: We report an additional four MAC cases treated by MMS. The accumulated data continue to confirm that, if the diagnosis of MAC is made early, and if the anatomic location is accessible to excision by MMS, a favorable outcome can be expected.
Authors:
Amor Khachemoune; Suzanne M Olbricht; Darlene S Johnson
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  International journal of dermatology     Volume:  44     ISSN:  0011-9059     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-08     Completed Date:  2005-10-25     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  507-12     Citation Subset:  IM    
Affiliation:
Georgetown University Medical Center, Division of Dermatology, Washington, DC, USA. amorkh@pol.net
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Carcinoma, Skin Appendage / diagnosis,  surgery*
Facial Neoplasms / diagnosis,  surgery*
Female
Humans
Male
Middle Aged
Mohs Surgery*
Scalp / pathology,  surgery*
Skin Neoplasms / diagnosis,  surgery*
Surgical Flaps

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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