Document Detail

Microcystic adnexal carcinoma involving a large portion of the face: when is surgery not reasonable?
MedLine Citation:
PMID:  16416625     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We report a case of microcystic adnexal carcinoma (MAC) involving a large portion of the face, one of the largest of any MAC reported thus far in this area, and review the literature regarding the nature of the tumor and available treatments. We also review all of the reported cases of metastases and the possible role of radiation in the etiopathogenesis of this tumor. OBJECTIVE: To review the literature about what is known about therapy for MAC and what options are available to patients who have this disease. MATERIALS AND METHODS: Case report and review of the literature. RESULTS: Of the 274 cases of MAC thus far reported, there are 6 cases of metastases, only 1 of which resulted in death. CONCLUSION: Mohs surgery should be the treatment of choice for this tumor; however, when extirpation entails sufficiently large morbidity, given the low rate of metastases and mortality, observation is a reasonable alternative.
Daniel Brian Eisen; David Zloty
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  31     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2006-01-18     Completed Date:  2006-02-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1472-7; discussion 1478     Citation Subset:  IM    
Department of Dermatology, University of California, Davis Medical Center, Sacramento, California 95818, USA.
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MeSH Terms
Carcinoma, Skin Appendage / pathology*,  surgery
Facial Neoplasms / pathology*,  surgery
Middle Aged
Mohs Surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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