| Microculture model studies on the effect of sorbic acid on Penicillium chrysogenum, Cladosporium cladosporioides and Ulocladium atrum at different pH levels. | |
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MedLine Citation:
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PMID: 8444649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The minimum growth-inhibitory concentration of sorbic acid has been determined for Penicillium chrysogenum, Cladosporium cladosporioides and Ulocladium atrum at pH 4.1-7.6 by using a microculture technique. This technique had earlier been applied to bacteria and Candida albicans and gave very reliable minimum inhibitory values. This investigation has shown that it is suitable also for determination of mould growth. The minimum inhibitory concentrations of sorbic acid were at the tested pH levels 1-230 mmol l-1 for P. chrysogenum, 0.3-18.0 mmol l-1 for C. cladosporioides and 0.2-33.0 mmol l-1 for U. atrum. A mathematical model for combined inhibition by dissociated and undissociated acid, which gave a good description of the minimum inhibitory concentration data earlier obtained for bacteria and Candida albicans, was suitable also for moulds. Both dissociated and undissociated acid contributed to growth inhibition. |
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Authors:
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I M Skirdal; T Eklund |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of applied bacteriology Volume: 74 ISSN: 0021-8847 ISO Abbreviation: J. Appl. Bacteriol. Publication Date: 1993 Feb |
Date Detail:
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Created Date: 1993-04-06 Completed Date: 1993-04-06 Revised Date: 2000-12-18 |
Medline Journal Info:
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Nlm Unique ID: 7503050 Medline TA: J Appl Bacteriol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 191-5 Citation Subset: IM |
Affiliation:
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MATFORSK, Norwegian Food Research Institute, Osloveien, As. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cladosporium
/
drug effects*,
growth & development Dose-Response Relationship, Drug Hydrogen-Ion Concentration Mitosporic Fungi / drug effects*, growth & development Models, Biological Penicillium chrysogenum / drug effects*, growth & development Regression Analysis Sorbic Acid / pharmacology* |
| Chemical | |
Reg. No./Substance:
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110-44-1/Sorbic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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