Document Detail


Microcolumn size-exclusion chromatography coupled with electrospray ionization mass spectrometry.
MedLine Citation:
PMID:  10220917     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Microcolumn (250 x 0.5 mm I.D.) size-exclusion chromatography was implemented for the separation of polydisperse mixtures prior to electrospray ionization (ESI) mass spectrometric detection. An improved separation, compared to conventional-bore SEC, was demonstrated upon coupling with ESI quadrupole ion-trap mass spectrometry and a Fourier transform ion cyclotron resonance instrument for the separation of individual oligomers present in octylphenoxypoly(ethoxy)ethanol.
Authors:
L Prokai; D J Aaserud; W J Simonsick
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of chromatography. A     Volume:  835     ISSN:  0021-9673     ISO Abbreviation:  J Chromatogr A     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-06-02     Completed Date:  1999-06-02     Revised Date:  2009-01-15    
Medline Journal Info:
Nlm Unique ID:  9318488     Medline TA:  J Chromatogr A     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  121-6     Citation Subset:  IM    
Affiliation:
University of Florida, College of Pharmacy, Center for Drug Discovery, Gainesville 32610-0497, USA.
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MeSH Terms
Descriptor/Qualifier:
Chromatography, Gel / instrumentation*
Fourier Analysis
Mass Spectrometry / instrumentation*
Octoxynol / chemistry
Grant Support
ID/Acronym/Agency:
S10 RR12023/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
9002-93-1/Octoxynol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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