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Microcirculation and macrocirculation in cardiac surgical patients.
MedLine Citation:
PMID:  22720146     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Background. The aim of our study was to investigate the relationship between microcirculatory alterations after open cardiac surgery, macrohemodynamics, and global indices of organ perfusion. Methods. Patients' microcirculation was assessed with near-infrared spectroscopy (NIRS) and the vascular occlusion technique (VOT). Results. 23 patients undergoing open cardiac surgery (11 male/12 female, median age 68 (range 28-82) years, EuroSCORE 6 (1-12)) were enrolled in the study. For pooled data, CI correlated with the tissue oxygen consumption rate as well as the reperfusion rate (r = 0.56, P < 0.001 and r = 0.58, P < 0.001, resp.). In addition, both total oxygen delivery (DO(2), mL/min per m(2)) and total oxygen consumption (VO(2), mL/min per m(2)) also correlated with the tissue oxygen consumption rate and the reperfusion rate. The tissue oxygen saturation of the thenar postoperatively correlated with the peak lactate levels during the six hour monitoring period (r = 0.50, P < 0.05). The tissue oxygen consumption rate (%/min) and the reperfusion rate (%/min), as derived from the VOT, were higher in survivors compared to nonsurvivors for pooled data [23 (4-54) versus 20 (8-38) P < 0.05] and [424 (27-1215) versus 197 (57-632) P < 0.01], respectively. Conclusion. Microcirculatory alterations after open cardiac surgery are related to macrohemodynamics and global indices of organ perfusion.
Elli-Sophia Tripodaki; Athanasios Tasoulis; Antigoni Koliopoulou; Ioannis Vasileiadis; Leonidas Vastardis; Giorgos Giannis; Mihalis Argiriou; Christos Charitos; Serafim Nanas
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Publication Detail:
Type:  Journal Article     Date:  2012-06-05
Journal Detail:
Title:  Critical care research and practice     Volume:  2012     ISSN:  2090-1313     ISO Abbreviation:  Crit Care Res Pract     Publication Date:  2012  
Date Detail:
Created Date:  2012-06-21     Completed Date:  2012-08-23     Revised Date:  2013-03-04    
Medline Journal Info:
Nlm Unique ID:  101539357     Medline TA:  Crit Care Res Pract     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  654381     Citation Subset:  -    
First Critical Care Department, Evangelismos Hospital, National and Kapodistrian University of Athens, Ypsilantou 45-47, 106 75 Athens, Greece.
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