Document Detail


Microchip-based electrochemical detection for monitoring cellular systems.
MedLine Citation:
PMID:  23340999     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The use of microchip devices to study cellular systems is a rapidly growing research area. There are numerous advantages of using on-chip integrated electrodes to monitor various cellular processes. The purpose of this review is to give examples of advancements in microchip-based cellular analysis, specifically where electrochemistry is used for the detection scheme. These examples include on-chip detection of single-cell quantal exocytosis, electrochemical analysis of intracellular contents, the ability to integrate cell culture/immobilization with electrochemistry, and the use of integrated electrodes to ensure cell confluency in longer-term cell culture experiments. A perspective on future trends in this area is also given.
Authors:
Alicia S Johnson; Asmira Selimovic; R Scott Martin
Related Documents :
18634089 - High frequency production of embryos from liquid flask cultures of oilseed rape.
10217179 - Two-dimensional electrophoresis of cereus peruvianus (cactaceae) callus tissue proteins.
24464079 - Medium optimization for the production of anti-cyanobacterial substances by streptomyce...
15449019 - Flow cytometric analysis of protein content in taxus protoplasts and single cells as co...
16972199 - Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared...
11909629 - Production of taxoids with biological activity by plants and callus culture from select...
9264029 - Partial anatomical and physiological characterization and dissociated cell culture of t...
281699 - Fibrinogen synthesis in serum-free hepatocyte cultures: stimulation by glucocorticoids.
21906449 - Application of melanocytes and bone marrow mesenchymal stem cells in tissue engineered ...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2013-01-23
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  405     ISSN:  1618-2650     ISO Abbreviation:  Anal Bioanal Chem     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-15     Completed Date:  2013-08-28     Revised Date:  2014-04-02    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  3013-20     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cells / chemistry*
Electrochemical Techniques / instrumentation,  methods*
Humans
Microchip Analytical Procedures / instrumentation,  methods*
Grant Support
ID/Acronym/Agency:
R15 GM084470/GM/NIGMS NIH HHS; R15GM084470-03/GM/NIGMS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Adenosine signaling during acute and chronic disease states.
Next Document:  Sweeteners from plants-with emphasis on Stevia rebaudiana (Bertoni) and Siraitia grosvenorii (Swingl...