| Microcephaly and early-onset nephrotic syndrome--confusion in Galloway-Mowat syndrome. | |
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MedLine Citation:
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PMID: 8747110 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a 2-year-old girl with nephrotic syndrome, microcephaly, seizures and psychomotor retardation. Histological studies of a renal biopsy revealed focal glomerular sclerosis with mesangiolysis and capillary microaneurysms. Dysmorphic features were remarkable: abnormal-shaped skull, coarse hair, narrow forehead, large low-set ears, almond-shaped eyes, low nasal bridge, pinched nose, thin lips and micrognathia. Cases with this rare combination of microcephaly and early onset of nephrotic syndrome with various neurological abnormalities have been reported. However, clinical manifestations and histological findings showed a wide variation, and there is a lot of confusion in this syndrome. We therefore reviewed the previous reports and propose a new classification of this syndrome. |
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Authors:
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H Sano; A Miyanoshita; N Watanabe; Y Koga; Y Miyazawa; Y Yamaguchi; Y Fukushima; N Itami |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric nephrology (Berlin, Germany) Volume: 9 ISSN: 0931-041X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 1995 Dec |
Date Detail:
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Created Date: 1996-10-09 Completed Date: 1996-10-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 711-4 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Nikko Memorial Hospital, Muroran, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child, Preschool Diagnosis, Differential Face / abnormalities Female Glomerulosclerosis, Focal Segmental / diagnosis, pathology Humans Kidney / pathology Mental Retardation / diagnosis* Microcephaly / diagnosis* Nephrotic Syndrome / diagnosis*, pathology Pedigree Seizures / diagnosis* Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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