Document Detail


Microcephaly, distinctive facies, single atrium, postaxial polydactyly, skeletal defects and mental retardation: a new familial faciocardiomelic syndrome?
MedLine Citation:
PMID:  17159509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three siblings with postaxial polydactyly type A, congenital heart defect (single atrium), mental retardation, microcephaly, a distinctive facial appearance, skeletal anomalies and neonatal macrosomy were studied. Comparison with other cardiomelic syndromes previously described in the literature lead us to conclude that this is a new faciocardiomelic syndrome probably inherited as an autosomal recessive trait.
Authors:
José Elías García-Ortiz; Diana García-Cruz; Ingrid Patricia Dávalos; Zamira Nazará; María Olga García-Cruz; Víctor Castañeda; Leonel Gutiérrez-Mendivil; Jose Sánchez-Corona
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical dysmorphology     Volume:  16     ISSN:  0962-8827     ISO Abbreviation:  Clin. Dysmorphol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-12     Completed Date:  2007-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9207893     Medline TA:  Clin Dysmorphol     Country:  England    
Other Details:
Languages:  eng     Pagination:  15-20     Citation Subset:  IM    
Affiliation:
Divisions of Genetics, University of Guadalajara; Guadalajara, Mexico.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics*,  pathology*
Adolescent
Child
Craniofacial Dysostosis / genetics,  pathology
Female
Genes, Recessive*
Heart Atria / pathology
Heart Defects, Congenital / genetics,  pathology
Humans
Limb Deformities, Congenital / genetics,  pathology
Male
Mental Retardation / genetics,  pathology
Microcephaly / genetics,  pathology
Pedigree
Quantitative Trait Loci*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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