| Microbubbles of Air may Occur in the Organs of Hemodialysis Patients. | |
| | |
MedLine Citation:
|
PMID: 22236622 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
During hemodialysis (HD), blood that passes the dialysis device gets loaded with microbubbles (MB) of air that are returned to the patient without inducing an alarm. The aim with this study was to clarify if these signals are due to microembolies of air, clots, or artifacts, by histopathology of autopsy material of HD patients. These first results are from a patient on chronic HD. Due to pulmonary edema he was ultrafiltered. Within 30 minutes after the start, he suffered from a cardiac arrest and died. Autopsy verified the clinical findings. Microscopic investigation verified microembolies of air that were surrounded by fibrin in the lungs, brain, and heart. The study verified that MBs can enter the blood during HD and are trapped in the lungs. In addition, MBs pass the pulmonary capillaries and enter the arterial part of the body and are dispersed throughout the body. This can contribute to organ damage and be part of the poor prognoses seen in HD patients. Data support the importance to reduce MBs in the dialysis circuit. |
| | |
Authors:
|
Bernd Stegmayr; Thomas Brännström; Ulf Forsberg; Per Jonson; Christofer Stegmayr; Johan Hultdin |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-10 |
Journal Detail:
|
Title: ASAIO journal (American Society for Artificial Internal Organs : 1992) Volume: - ISSN: 1538-943X ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-12 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9204109 Medline TA: ASAIO J Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
*Department of Public Health and Clinical Medicine, Medicine, Umea University, Umea, Sweden †Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden ‡Department of Clinical Chemistry, Umea University, Umea, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clearance, Distribution Volume, and Dialyzer Mass Area Transport Coefficient of Glucose in Whole Blo...
Next Document: Optimal Timing Algorithms of Para-Aortic Counterpulsation Device: An Animal Study.