| [Microbiota and irritable bowel syndrome]. | |
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MedLine Citation:
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PMID: 20889005 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Irritable bowel syndrome (IBS) is a multifactorial disease during which the pathophysiological role of the gut microbiota has been recently highlighted. In almost 20% of the patients, IBS is clearly a post-infectious IBS as a consequence of an acute bacterial gastroenteritis. Some papers have reported an abnormal colonic fermentation in IBS patients that could explain symptoms such as bloating and be one of the factors triggering visceral hypersensitivity. More recently, significant differences in the composition of both the luminal and mucosa-associated microbiota have been reported between both IBS patients and healthy controls and IBS subgroups while some arguments exist for a small intestinal overgrowth in a subset of IBS patients. All these arguments for a deleterious role of the gut microbiota lead to the actual discuss to consider new therapeutic options, including mainly pre- and probiotics and maybe antibiotics. |
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Authors:
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P Ducrotté |
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Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Gastroentérologie clinique et biologique Volume: 34 Suppl 1 ISSN: 2210-7401 ISO Abbreviation: Gastroenterol. Clin. Biol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-10-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7704825 Medline TA: Gastroenterol Clin Biol Country: France |
Other Details:
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Languages: fre Pagination: S52-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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ADEN EA 4311/IFRMP 23, Department of Hepatogastroenterology and Nutrition, Regional University Hospital, Charles Nicolle Hospital, 1 Rue de Germont, Rouen Cedex, France. philippe.ducrotte@chu-rouen.fr |
Vernacular Title:
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Flore et syndrome de l’intestin irritable. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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