| Microbiological profile of septic complication in patients with cardiogenic shock following acute myocardial infarction (from the SHOCK study). | |
| | |
MedLine Citation:
|
PMID: 17350369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We sought to assess the microbiologic profile of patients with suspected sepsis who participated in the SHould we emergently revascularize Occluded Coronaries in cardiogenic shocK? (SHOCK) trial, a randomized controlled trial of early coronary revascularization in patients with cardiogenic shock complicating acute myocardial infarction. A protocol-mandated SEPSIS form was completed prospectively for 54 patients (18%) with fever or leukocytosis suggestive of sepsis. These patients were divided further into those with positive (n = 40) or negative (n = 14) culture results. The predominant pathogen isolated in patients with positive culture results was Staphylococcus aureus (32%), followed by Klebsiella pneumoniae and Pseudomonas aeruginosa. Patients with both positive and negative culture results had longer median durations of mechanical ventilation (p <0.001 and p = 0.02), intra-aortic balloon pump (IABP) support (p = 0.074 and p = 0.021), and hospital stay (p <0.001 and p = 0.048) than controls. Sepsis was predicted by both duration of IABP support (p = 0.007) and use of multiple central catheters (p = 0.026). In conclusion, clinical sepsis is common after cardiogenic shock complicating acute myocardial infarction, particularly in patients who received prolonged IABP support or had multiple central catheters. |
| | |
Authors:
|
Shun Kohsaka; Venu Menon; Kentaro Iwata; April Lowe; Lynn A Sleeper; Judith S Hochman; |
Related Documents
:
|
6349299 - Pharmacologic support in cardiogenic shock. 8417549 - Transthoracic defibrillation: effect of dual-pathway sequential pulse shocks and single... 12475849 - Clinical features and outcome of patients with direct percutaneous coronary interventio... 10525249 - Induction of ventricular fibrillation by t wave shocks: observations from monophasic ac... 17467139 - Shock outcome is related to prior rhythm and duration of ventricular fibrillation. 16099219 - Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. 16315829 - The usual causes of left ventricular outflow tract obstruction below the aortic valve i... 1516189 - Combined use of time and frequency domain variables in signal-averaged ecg as a predict... 8313439 - Preconditioning and reperfusion arrhythmias in the isolated rat heart: true protection ... |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial Date: 2007-01-16 |
Journal Detail:
|
Title: The American journal of cardiology Volume: 99 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2007 Mar |
Date Detail:
|
Created Date: 2007-03-12 Completed Date: 2007-04-26 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 802-4 Citation Subset: AIM; IM |
Affiliation:
|
Division of Cardiology, Columbia University, College of Physicians and Surgeons, New York, New York, USA. sk2798@columbia.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Bacteremia / blood, epidemiology*, etiology, microbiology Catheterization / adverse effects Female Gram-Negative Bacteria / isolation & purification* Humans Intensive Care Units Intra-Aortic Balloon Pumping / adverse effects Klebsiella pneumoniae / isolation & purification Length of Stay Male Middle Aged Pseudomonas aeruginosa / isolation & purification Randomized Controlled Trials as Topic Respiration, Artificial / adverse effects Shock, Cardiogenic / complications* Staphylococcus aureus / isolation & purification* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A practical approach with outcome for the prognostic assessment of non-ST-segment elevation chest pa...
Next Document: Effect of colchicine (0.5 mg twice daily) on high-sensitivity C-reactive protein independent of aspi...