| Microbiological assessment of the ultraviolet screening effect of sunscreen preparations. | |
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MedLine Citation:
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PMID: 18818849 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was the development of a microbiological method for the assessment of the ultraviolet (UV) screening effect of sunscreen preparations and determination of their sun protection factor. The method is based on the lethal effect of UV radiation on Escherichia coli (E. coli ) and the protective ability of sunscreens. The time of UV exposure required for the reduction of the E. coli viable count by 90% (decimal reduction time, DRT) was used as the photoprotection assessment parameter. The method was tested by assessing the effect of selected experimental variables on the DRT. The suitability of the method as a quality control tool for sunscreen preparations was then checked by assessing the influence of selected formulation variables on the photoprotective effect of a series of o/w emulsion formulations with different compositions. The method proved valid for detecting changes in the photoprotective effect of a market sunscreen product as a result of modifying experimental conditions. It also proved valid for ranking market sunscreen products according to their UV screening effect. Equally important, the method could successfully detect changes in the photoprotective effect of sunscreen test formulations as a function of the concentration and type of the sunscreen agents. |
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Authors:
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Yasmine Gomaa; Elsayed Aboulmagd; Nabila A Boraei; Inas A Darwish; Labiba K El-Khordagui |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of cosmetic science Volume: 59 ISSN: 1525-7886 ISO Abbreviation: J Cosmet Sci Publication Date: 2008 Jul-Aug |
Date Detail:
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Created Date: 2008-09-26 Completed Date: 2008-10-16 Revised Date: 2010-07-26 |
Medline Journal Info:
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Nlm Unique ID: 9814276 Medline TA: J Cosmet Sci Country: United States |
Other Details:
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Languages: eng Pagination: 291-302 Citation Subset: IM |
Affiliation:
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Department of Pharmaceutics, University of Alexandria, El-Khartoum Square, Azarita, Alexandria 21521, Egypt. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Benzimidazoles
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pharmacology Benzophenones / pharmacology Drug Evaluation, Preclinical / methods Escherichia coli / growth & development, radiation effects* Reproducibility of Results Sulfonic Acids / pharmacology Sunscreening Agents / pharmacology* Titanium / pharmacology Ultraviolet Rays / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Benzimidazoles; 0/Benzophenones; 0/Sulfonic Acids; 0/Sunscreening Agents; 0/ensulizole; 131-57-7/oxybenzone; 13463-67-7/titanium dioxide; 7440-32-6/Titanium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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