Document Detail

Microbiologic evaluation of commercial probiotics.
MedLine Citation:
PMID:  11918274     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate contents of commercial probiotic products marketed for veterinary or human administration. DESIGN: Microbiologic culture assay. SAMPLE POPULATION: 8 veterinary probiotics and 5 human probiotics. PROCEDURE: Quantitative bacteriologic culture was performed on all products, and isolates were identified via biochemical characteristics. Comparison of actual contents versus label claims was performed. RESULTS: Label descriptions of organisms and concentrations accurately described the actual contents of only 2 of 13 products. Five veterinary products did not specifically list their contents. Most products contained low concentrations of viable organisms. Five products did not contain 1 or more of the stated organisms, and 3 products contained additional species. Some products contained organisms with no reported probiotic effects; some of these organisms could be pathogens. CONCLUSIONS AND CLINICAL RELEVANCE: Most commercial veterinary probiotic preparations are not accurately represented by label claims. Quality control appears to be poor for commercial veterinary probiotics.
J Scott Weese
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  220     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-03-28     Completed Date:  2002-07-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  794-7     Citation Subset:  IM    
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada.
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MeSH Terms
Bacteria / growth & development*
Colony Count, Microbial / veterinary
Drug Labeling / standards
Probiotics / standards*
Quality Control
Comment In:
J Am Vet Med Assoc. 2002 Jun 1;220(11):1610-1; author reply 1611-2   [PMID:  12051493 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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