| Microbicidal and cytotoxic effects of functional water in vitro. | |
| | |
MedLine Citation:
|
PMID: 20806093 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Several kinds of functional water are used in the fields of food hygiene and medicine. The purpose of this study was to evaluate both the disinfection and cytotoxic effects of functional water in comparison with commonly used root canal irrigants such as sodium hypochlorite solution and hydrogen peroxide solution. METHOD AND MATERIALS: Three kinds of functional water were examined: alkaline electrolysis water (AEW), strong acid electrolyzed water (SAEW), and hypochlorous acid water (HAW). The disinfection effect was studied using Enterococcus faecalis and Candida albicans with or without organic substance. Each kind of functional water was applied to samples, and the colony formation was evaluated. The cytotoxic effect was evaluated by mitogenic assay (MTT) and alkaline phosphatase (ALPase) activity in pulp cells. RESULTS: SAEW and HAW showed microbicidal effects in the presence of organic substance, with an effect almost similar to sodium hypochlorite solution. AEW did not show any microbicidal effect. SAEW, AEW, and HAW at 10- and 1,000-times dilution did not inhibit the MTT assay and ALPase activity. The cytotoxicity of SAEW and HAW against pulp cells was mild compared to that of sodium hypochlorite solution. CONCLUSION: Functional water like SAEW and HAW have a good microbicidal effect under existing organic substance and are also mild to pulp cells. |
| | |
Authors:
|
Kazuhiro Gomi; Tomohiko Makino; Shinichi Suzuki; Masako Hasegawa; Nobuko Maeda; Takashi Arai |
Related Documents
:
|
18977503 - In vitro toxicity of surface water disinfected by different sequential treatments. 17278743 - Removal effect on mesocyclops leukarti and mutagenicity with chlorine dioxide. 10936453 - Deplasticizing or etching of epoxy sections with different concentrations of sodium eth... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Quintessence international (Berlin, Germany : 1985) Volume: 41 ISSN: 1936-7163 ISO Abbreviation: Quintessence Int Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-08-31 Completed Date: 2010-12-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0342677 Medline TA: Quintessence Int Country: Germany |
Other Details:
|
Languages: eng Pagination: e166-72 Citation Subset: D |
Affiliation:
|
Department of Endodontics and Periodontics, Tsurumi University, School of Dental Medicine, Yokohama, Japan. gomi-k@tsurumi-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alkalies Alkaline Phosphatase / analysis Candida albicans / drug effects Cell Culture Techniques Cell Proliferation / drug effects Cell Survival / drug effects Colony Count, Microbial Coloring Agents / diagnostic use Dental Pulp / cytology, drug effects* Disinfectants / pharmacology*, toxicity Enterococcus faecalis / drug effects Humans Hydrogen Peroxide / pharmacology, toxicity Hypochlorous Acid / pharmacology, toxicity Root Canal Irrigants / pharmacology*, toxicity Sodium Hypochlorite / pharmacology, toxicity Tetrazolium Salts / diagnostic use Thiazoles / diagnostic use Water |
| Chemical | |
Reg. No./Substance:
|
0/Alkalies; 0/Coloring Agents; 0/Disinfectants; 0/Root Canal Irrigants; 0/Tetrazolium Salts; 0/Thiazoles; 0/superoxidized water; 298-93-1/thiazolyl blue; 7681-52-9/Sodium Hypochlorite; 7722-84-1/Hydrogen Peroxide; 7732-18-5/Water; 7790-92-3/Hypochlorous Acid; EC 3.1.3.1/Alkaline Phosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of three strains of diabetic rats with respect to the rate at which retinopathy and tacti...
Next Document: Bond strengths of an epoxy resin-based fiber post with four adhesive systems.