Document Detail


Microbial drug discovery: 80 years of progress.
MedLine Citation:
PMID:  19132062     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Microbes have made a phenomenal contribution to the health and well-being of people throughout the world. In addition to producing many primary metabolites, such as amino acids, vitamins and nucleotides, they are capable of making secondary metabolites, which constitute half of the pharmaceuticals on the market today and provide agriculture with many essential products. This review centers on these beneficial secondary metabolites, the discovery of which goes back 80 years to the time when penicillin was discovered by Alexander Fleming.
Authors:
Arnold L Demain; Sergio Sanchez
Publication Detail:
Type:  Historical Article; Journal Article; Review     Date:  2009-01-09
Journal Detail:
Title:  The Journal of antibiotics     Volume:  62     ISSN:  0021-8820     ISO Abbreviation:  J. Antibiot.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-10-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151115     Medline TA:  J Antibiot (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  5-16     Citation Subset:  IM    
Affiliation:
Research Institute for Scientists Emeriti, Drew University, Madison, NJ 07940, USA. ademain@drew.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Bacterial Agents / chemical synthesis,  history*,  pharmacology*
Biological Products / chemistry
Drug Resistance, Bacterial
Drug Resistance, Fungal
Drug Resistance, Microbial
History, 20th Century
History, 21st Century
Humans
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Biological Products

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