| Microbial degradation of poly(amino acid)s. | |
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MedLine Citation:
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PMID: 15244426 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Natural poly(amino acid)s are a group of poly(ionic) molecules (ionomers) with various biological functions and putative technical applications and play, therefore, an important role both in nature and in human life. Because of their biocompatibility and their synthesis from renewable resources, poly(amino acid)s may be employed for many different purposes covering a broad spectrum of medical, pharmaceutical, and personal care applications as well as the domains of agriculture and of environmental applications. Biodegradability is one important advantage of naturally occurring poly(amino acid)s over many synthetic polymers. The intention of this review is to give an overview about the enzyme systems catalyzing the initial steps in poly(amino acid) degradation. The focus is on the naturally occurring poly(amino acid)s cyanophycin, poly(epsilon-L-lysine) and poly(gamma-glutamic acid); but biodegradation of structurally related synthetic polyamides such as poly(aspartic acid) and nylons, which are known from various technical applications, is also included. |
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Authors:
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Martin Obst; Alexander Steinbüchel |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Biomacromolecules Volume: 5 ISSN: 1525-7797 ISO Abbreviation: Biomacromolecules Publication Date: 2004 Jul-Aug |
Date Detail:
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Created Date: 2004-07-12 Completed Date: 2005-02-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100892849 Medline TA: Biomacromolecules Country: United States |
Other Details:
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Languages: eng Pagination: 1166-76 Citation Subset: IM |
Affiliation:
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Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität Münster, Corrensstrasse 3, 48149 Münster, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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chemistry,
metabolism* Bacteria / metabolism* Biodegradation, Environmental Fungi / metabolism Humans Molecular Structure Nylons / chemistry, metabolism Peptides / chemistry, metabolism* Plant Proteins / chemistry, metabolism Polyglutamic Acid / chemistry, metabolism Polylysine / chemistry, metabolism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Nylons; 0/Peptides; 0/Plant Proteins; 0/cyanophycin; 25104-18-1/Polylysine; 25513-46-6/Polyglutamic Acid; 26063-13-8/polyaspartate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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