| Microbial biotransformations of bile acids as detected by electrospray mass spectrometry. | |
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MedLine Citation:
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PMID: 23319120 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Many current experiments investigating the effects of diet, dietary supplements, and pre- and probiotics on the intestinal environments do not take into consideration the potential for using bile salts as markers of environmental change. Intestinal bacteria in vertebrates can metabolize bile acids into a number of different structures, with deamidation, hydroxyl group oxidation, and hydroxyl group elimination. Fecal bile acids are readily available to sample and contain a considerable structural complexity that directly relates to intestinal morphology, bile acid residence time in the intestine, and the species of microbial forms in the intestinal tract. Here we offer a classification scheme that can serve as an initial guide to interpret the different bile acid patterns expressed in vertebrate feces. |
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Authors:
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Lee R Hagey; Matthew D Krasowski |
Publication Detail:
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Type: Journal Article Date: 2013-01-01 |
Journal Detail:
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Title: Advances in nutrition (Bethesda, Md.) Volume: 4 ISSN: 2156-5376 ISO Abbreviation: Adv Nutr Publication Date: 2013 |
Date Detail:
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Created Date: 2013-01-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101540874 Medline TA: Adv Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 29-35 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of California at San Diego, CA. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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