| Microbial biosurfactants and hydrolytic enzymes mediates in situ development of stable supra-molecular assemblies in fatty acids released from triglycerides. | |
| | |
MedLine Citation:
|
PMID: 20359870 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The present study demonstrates in situ formation of multilamellar stable vesicles (MLSVs) of fatty acids released during the growth of microorganisms in the presence of triglycerides. Release of lipase during initial phase of growth hydrolyzes the triglycerides and release free fatty acids (mono or diglycerides) and glycerol. By extending the growth and the prevailing composition of media (unspent nutrients, salts, pH of the medium, biosurfactants, fatty acids, glycerol) and agitation transforms free fatty acids to MLSV of both cylindrical and spherical macroscopic structures via micelle formation with in 240h of incubation. Cross-sectional view and SEM analysis of macroscopic structures reveal the existence of continuous multilayering. Thermo-gravimetric analysis illustrates the stability of the vesicles. FT-IR analysis emphasizes the presence of amide linkages, responsible for self-assembly processes. Schematic representation of formation of MLSV demonstrated for further understanding. Additional exploration on MLSV formation in arteries and the relationship between MLSV and in situ plaque formation by the components of blood in the arteries are schematically explained and submitted as supporting information (SI-2). |
| | |
Authors:
|
Arumugam Gnanamani; V Kavitha; N Radhakrishnan; G Sekaran; G Suseela Rajakumar; A B Mandal |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-03-12 |
Journal Detail:
|
Title: Colloids and surfaces. B, Biointerfaces Volume: 78 ISSN: 1873-4367 ISO Abbreviation: Colloids Surf B Biointerfaces Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-05-03 Completed Date: 2010-08-20 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9315133 Medline TA: Colloids Surf B Biointerfaces Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 200-7 Citation Subset: IM |
Copyright Information:
|
2010 Elsevier B.V. All rights reserved. |
Affiliation:
|
Microbiology Division, Central Leather Research Institute, (CSIR, New Delhi), Adyar, Chennai 20, Tamil Nadu, India. agmani_2000@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bacillus
/
chemistry*,
metabolism,
ultrastructure Bacterial Proteins / metabolism Fatty Acids, Nonesterified / chemistry*, metabolism Hydrogen-Ion Concentration Hydrolysis Lipase / metabolism Liposomes / chemistry, metabolism, ultrastructure Microscopy, Electron, Scanning Spectroscopy, Fourier Transform Infrared Surface-Active Agents / chemistry*, metabolism Thermogravimetry Triglycerides / chemistry*, metabolism |
| Chemical | |
Reg. No./Substance:
|
0/Bacterial Proteins; 0/Fatty Acids, Nonesterified; 0/Liposomes; 0/Surface-Active Agents; 0/Triglycerides; EC 3.1.1.3/Lipase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Molecular characteristics of extended-spectrum beta-lactamase-producing Escherichia coli from the Ch...
Next Document: Protective effect of date palm fruit extract (Phoenix dactylifera L.) on dimethoate induced-oxidativ...