| Microbial asymmetric oxidation of 2-butyl-1,3-propanediol. | |
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MedLine Citation:
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PMID: 17453192 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Microbial asymmetric oxidation of 2-butyl-1,3-propanediol was investigated for an efficient synthesis of S- and R-enantiomers of 2-hydroxymethylhexanoic acid (2-HMHA). From an intensive survey of the stocked bacterial strains, Acetobacter pasteurianus IAM 12073 and Pseudomonas putida IFO 3738 were found to show the highest S- and R-2-HMHA-producing activity, respectively. Under optimized conditions, A. pasteurianus (351 mg dry cell weight) and P. putida (642 mg dry cell weight) cells produced 12.0 g l(-1) S-2-HMHA with 89% enantiomeric excess (e.e.) at 24 h of incubation and 5.1 g l(-1) R-2-HMHA with 94% e.e. at 35 h of incubation from 2-butyl-1,3-propanediol. |
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Authors:
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K Mitsukura; T Uno; T Yoshida; T Nagasawa |
Publication Detail:
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Type: Journal Article Date: 2007-04-24 |
Journal Detail:
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Title: Applied microbiology and biotechnology Volume: 76 ISSN: 0175-7598 ISO Abbreviation: Appl. Microbiol. Biotechnol. Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-08-01 Completed Date: 2007-09-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8406612 Medline TA: Appl Microbiol Biotechnol Country: Germany |
Other Details:
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Languages: eng Pagination: 61-5 Citation Subset: IM |
Affiliation:
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Department of Biomolecular Science, Faculty of Engineering, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetobacter
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metabolism* Biotransformation Oxidation-Reduction Propylene Glycol / metabolism* Pseudomonas putida / metabolism* |
| Chemical | |
Reg. No./Substance:
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57-55-6/Propylene Glycol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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