Document Detail


Microarray platforms for enzymatic and cell-based assays.
MedLine Citation:
PMID:  17325784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This tutorial review introduces the uninitiated to the world of microarrays (or so-called chips) and covers a number of basic concepts such as substrates and surfaces, printing and analysis. It then moves on to look at some newer applications of microarray technology, which include enzyme analysis (notably kinases and proteases) as well as the growing enchantment with so-called cell-based microarrays that offer a unique approach to high-throughput cellular analysis. Finally, it looks forwards and highlights future possible trends and directions in the microarray arena.
Authors:
Juan J Díaz-Mochón; Guilhem Tourniaire; Mark Bradley
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2006-10-16
Journal Detail:
Title:  Chemical Society reviews     Volume:  36     ISSN:  0306-0012     ISO Abbreviation:  Chem Soc Rev     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-27     Completed Date:  2007-04-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0335405     Medline TA:  Chem Soc Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  449-57     Citation Subset:  IM    
Affiliation:
School of Chemistry, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh, EH9 3JJ, UK.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cells, Cultured
Enzymes, Immobilized / chemistry*
Humans
Microarray Analysis / methods*
Chemical
Reg. No./Substance:
0/Enzymes, Immobilized

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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