| Microangiopathy of the brain and retina with hearing loss in a 50 year old woman: extending the spectrum of Susac's syndrome. | |
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MedLine Citation:
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PMID: 10209178 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 50 year old woman presented with a subacute onset of vertigo and diplopia followed by an encephalopathy with confusion, spasticity, ataxia, myoclonus, and multiple branch retinal arteriolar occlusions and unilateral sensorineural deafness. Brain biopsy confirmed multiple microinfarcts with no vasculitis. After the procedure she had a right iliofemoral deep vein thrombosis and was found to be heterozygous for the factor V Leiden mutation. She was treated with anticoagulants and made a marked recovery with no relapses 6 months after presentation. This case extends the age range at which Susac's syndrome can present, and raises the possibility that the condition may be associated with abnormalities of coagulation. |
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Authors:
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R A Barker; J R Anderson; P Meyer; D J Dick; N J Scolding |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neurology, neurosurgery, and psychiatry Volume: 66 ISSN: 0022-3050 ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 1999 May |
Date Detail:
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Created Date: 1999-05-25 Completed Date: 1999-05-25 Revised Date: 2008-11-20 |
Medline Journal Info:
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Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 641-3 Citation Subset: IM |
Affiliation:
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Department of Neurology, Norfolk and Norwich Health Care Trust, Brunswick Road, Norwich, Norfolk NR 1 3SR, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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pathology* Cerebral Arteries / pathology Cerebrovascular Disorders / pathology* Female Hearing Loss, Sensorineural / pathology* Humans Magnetic Resonance Imaging Middle Aged Retina / pathology* |
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