Document Detail


Microalbuminuria is associated with abnormal thoracic aortic mechanics in essential hypertension.
MedLine Citation:
PMID:  11018207     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a population of 162 patients with currently untreated essential hypertension, those with microalbuminuria (n = 75) had significantly impaired elastic properties of the proximal ascending thoracic aorta compared with their normoalbuminuric counterparts (n = 87), whereas urinary albumin excretion was a significant predictor of aortic mechanics in the entire population. Impaired aortic mechanics in microalbuminuric hypertensives were not fully accounted for by clustering of classic risk factors for atherosclerosis, and constitute a finding that may entail additional long-term cardiovascular risk in this subgroup of patients.
Authors:
C P Tsioufis; S G Lambrou; C I Stefanadis; D I Antoniadis; I E Kallikazaros; C E Pitsavos; P K Toutouzas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  86     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2000-11-01     Completed Date:  2000-11-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  797-801, A9     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, University of Athens, Hippokration Hospital, Greece.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Albuminuria / physiopathology*
Aorta, Thoracic / physiopathology*
Echocardiography
Humans
Hypertension / physiopathology*,  urine*
Middle Aged

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