| MicroRNAs: a new therapeutic frontier for muscle wasting in chronic kidney disease. | |
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MedLine Citation:
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PMID: 22846810 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Multiple microRNAs (miRs) are implicated in muscle cell differentiation and muscle mass regulation. Pharmacological agents targeting miR-486 and other miRs, involved in muscle mass regulation, could potentially be developed into therapeutic agents for muscle wasting. Muscle wasting is prevalent among patients with chronic kidney disease (CKD). Xu et al. showed that miR-486 mimetic ameliorated muscle wasting in mice with CKD. miR mimetics may represent a new therapeutic frontier for muscle wasting in CKD. |
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Authors:
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Robert H Mak; Wai W Cheung |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Kidney international Volume: 82 ISSN: 1523-1755 ISO Abbreviation: Kidney Int. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-07-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0323470 Medline TA: Kidney Int Country: United States |
Other Details:
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Languages: eng Pagination: 373-4 Citation Subset: IM |
Affiliation:
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Division of Pediatric Nephrology, University of California, San Diego, Rady Children's Hospital, San Diego, California, USA. |
Export Citation:
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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