| MicroRNAs in the regeneration of skeletal muscle . | |
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MedLine Citation:
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PMID: 23276946 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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MicroRNAs (miRNAs) have emerged as critical regulators of numerous biological processes by modulating gene expression at the post-transcriptional level. The discovery of miRNAs as new and important regulators of gene expression is expected to broaden our biological understanding of the regulatory mechanism in muscle by adding another dimension of regulation to the diversity and complexity of gene-regulatory networks. Exercise-induced skeletal muscle injury and repair have always been among the highlights of research in sports medicine. However, many mechanism problems that occur during regeneration and repair in the aftermath of skeletal muscle injury remain unsolved. It has become increasingly clear that the regeneration of skeletal muscle development involve regulation by miRNAs. In the last few years the field has seen a rapid expansion of our knowledge of miRNAs in the regeneration of skeletal muscle. This study reviews the miRNAs related with regeneration of skeletal muscle, and discuss the regulation of their expression in muscles, and emerging themes of miRNA regulation. |
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Authors:
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Xin Kai Yu; Qun Zuo |
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Publication Detail:
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Type: Journal Article Date: 2013-01-01 |
Journal Detail:
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Title: Frontiers in bioscience : a journal and virtual library Volume: 18 ISSN: 1093-4715 ISO Abbreviation: Front. Biosci. Publication Date: 2013 |
Date Detail:
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Created Date: 2013-01-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9709506 Medline TA: Front Biosci Country: United States |
Other Details:
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Languages: eng Pagination: 608-15 Citation Subset: IM |
Affiliation:
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Shanghai University of Sport,Shanghai, 200438, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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