| MicroRNAs and Glial Cell Development. | |
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MedLine Citation:
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PMID: 21555783 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Mounting evidence indicates that microRNAs (miRNAs) play important roles in the control of glial cell development in the central nervous system. Suppression of miRNA formation disrupts the initial generation of oligodendrocyte progenitor cells from the ventricular neuroprogenitor cells in the embryonic spinal cord. miRNAs also regulate the later events of oligodendrocyte development, including cell proliferation, maturation, and myelin formation. In addition, miRNAs are essential for the development of astrocytes, and inhibition of miRNA genesis completely blocks astrogliogenesis in the spinal cord. |
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Authors:
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Kang Zheng; Hong Li; Hao Huang; Mengsheng Qiu |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-9 |
Journal Detail:
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Title: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Volume: - ISSN: 1089-4098 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9504819 Medline TA: Neuroscientist Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Institute of Developmental and Regenerative Biology, Hangzhou Normal University, College of Life and Environmental Sciences, Hangzhou, Zhejiang, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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