Document Detail


MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration.
MedLine Citation:
PMID:  22821679     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: miR-221 overexpression accelerates hepatocyte proliferation. Pharmacological intervention targeting miR-221 may thus be therapeutically beneficial in liver failure by preventing apoptosis and by inducing liver regeneration.
Authors:
Qinggong Yuan; Komal Loya; Bhavna Rani; Selina Möbus; Asha Balakrishnan; Jutta Lamle; Toni Cathomen; Arndt Vogel; Michael P Manns; Michael Ott; Tobias Cantz; Amar Deep Sharma
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  57     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-08     Completed Date:  2013-03-04     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-310     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Association for the Study of Liver Diseases.
Affiliation:
Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, Germany.
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MeSH Terms
Descriptor/Qualifier:
Animals
Aryl Hydrocarbon Receptor Nuclear Translocator / metabolism
Cell Proliferation
Hepatectomy
Hepatocytes / physiology*
Liver Regeneration*
Mice
MicroRNAs / metabolism*
Chemical
Reg. No./Substance:
0/Arnt protein, mouse; 0/MIRN221 microRNA, mouse; 0/MicroRNAs; 138391-32-9/Aryl Hydrocarbon Receptor Nuclear Translocator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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