Document Detail


Micro-pattern-controlled local microtubule nucleation, transport and mesoscale organisation.
MedLine Citation:
PMID:  23294267     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Microtubule organisation in living cells is determined by spatial control of microtubule nucleation, their dynamic properties and transport by molecular motors. Here, we establish a new micro-pattern-guided method for controlling local microtubule nucleation by spatially confined immobilisation of a microtubule polymerase and show that these nucleated microtubules can be transported and organised in space by motor proteins. This assay provides a new platform for deciphering the principles underlying mesoscale microtubule organisation.
Authors:
Surajit Ghosh; Christian Hentrich; Thomas Surrey
Related Documents :
1114867 - A fine structural study of asexual stages of the murine coccidium eimeria ferrisi levin...
12177447 - Febrile temperatures induce cytoadherence of ring-stage plasmodium falciparum-infected ...
36617 - From extracellular to intracellular: the establishment of a symbiosis.
15639737 - How do malaria ookinetes cross the mosquito midgut wall?
3416337 - Localization of pigment-dispersing hormone (pdh) immunoreactivity in the central nervou...
8173047 - Cellular deformability of normoxic and hypoxic mammalian red blood cells.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-8
Journal Detail:
Title:  ACS chemical biology     Volume:  -     ISSN:  1554-8937     ISO Abbreviation:  ACS Chem. Biol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101282906     Medline TA:  ACS Chem Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Capillary versus venous haemoglobin determination in the assessment of healthy blood donors.
Next Document:  Dirichlet mixtures, the Dirichlet process, and the structure of protein space.