Document Detail


Micro indirect hemagglutination test for Cytomegalovirus.
MedLine Citation:
PMID:  4322278     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In an effort to obtain the flexibility and ease of performance of a rapid, serological test for detection of cytomegalovirus antibody, the indirect hemagglutination (IHA) technique was investigated by using a microserological system. Antigens were prepared from tissue cultures of infected human fibroblasts. The specificity of the cytomegalovirus antibody response detected by the IHA test correlated well with the standard neutralization test. The IHA method was more sensitive than the complement fixation test in detecting antibody in congenitally infected newborns. There appeared to be some heterologous antibody response with Herpesvirus hominis or varicella virus infections. The IHA test pattern was found to be very stable with excellent persistence of agglutination.
Authors:
D A Fuccillo; F Moder; R G Traub; S Hensen; J L Sever
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Applied microbiology     Volume:  21     ISSN:  0003-6919     ISO Abbreviation:  Appl Microbiol     Publication Date:  1971 Jan 
Date Detail:
Created Date:  1971-03-12     Completed Date:  1971-03-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7605802     Medline TA:  Appl Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  104-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Antigen-Antibody Reactions
Complement Fixation Tests
Cross Reactions
Culture Techniques
Cytomegalovirus / immunology*
Fibroblasts
Hemagglutination Tests*
Herpesvirus 3, Human / immunology
Humans
Immune Sera
Infant
Infant, Newborn
Neutralization Tests
Simplexvirus / immunology
Temperature
Time Factors
Chemical
Reg. No./Substance:
0/Immune Sera
Comments/Corrections

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