Document Detail

Metronidazole-induced encephalopathy.
MedLine Citation:
PMID:  15450780     Owner:  NLM     Status:  MEDLINE    
We report the clinical, neuropsychological, and neuroimaging findings of two patients of diffuse encephalopathy associated with the use of metronidazole. Both patients showed characteristic abnormalities on magnetic resonance imaging (MRI) with diffusion weighted imaging (DWI) and recovered incompletely after the discontinuation of metronidazole. We also suggest that MRI with DWI may be useful in the diagnosis of metronidazole-induced encephalopathy, and that they have a role in the prediction of prognosis.
Dong Wook Kim; Jong-Moo Park; Byung-Woo Yoon; Min Jae Baek; Jung Eun Kim; SangYun Kim
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  224     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-28     Completed Date:  2004-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  107-11     Citation Subset:  IM    
Clinical Neuroscience Center, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, 464-707, South Korea.
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MeSH Terms
Anti-Infective Agents / toxicity
Attention / physiology
Brain Mapping
Diffusion Magnetic Resonance Imaging / methods
Mental Processes / physiology
Metronidazole / toxicity*
Middle Aged
Neuropsychological Tests / statistics & numerical data
Wernicke Encephalopathy / chemically induced*,  diagnosis,  pathology,  physiopathology
Reg. No./Substance:
0/Anti-Infective Agents; 443-48-1/Metronidazole

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