Document Detail


Metronidazole and the immune system.
MedLine Citation:
PMID:  21699075     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Metronidazole (MTZ) is a nitroimidazole antibiotic used mainly for the treatment of infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa. Distinct from its antibiotic, amoebicidal, and antiprotozoal effects, MTZ displays immunopharmacological behaviour. This review outlines multiple effects of MTZ on different aspects of immunity, including innate and acquired immunity, and also highlights the immunopharmacological behaviour of MTZ in terms of its relevance to inflammation, delayed type hypersensitivity (DTH) and graft versus host disease (GVHD).
Authors:
L Shakir; A Javeed; M Ashraf; A Riaz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Die Pharmazie     Volume:  66     ISSN:  0031-7144     ISO Abbreviation:  Pharmazie     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-06-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9800766     Medline TA:  Pharmazie     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  393-8     Citation Subset:  IM    
Affiliation:
Department of Pharmacology & Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan.
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