| Metoclopramide-induced raised intracranial pressure after head injury. | |
| | |
MedLine Citation:
|
PMID: 11907399 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report a case of raised intracranial pressure in a head-injured patient following the intravenous administration of metoclopramide. The patient required admission to an intensive care unit after a road traffic accident. A CT scan of the head was consistent with diffuse axonal injury and supportive management included intracranial pressure monitoring. On the third day after admission, intravenous metoclopramide 10mg was administered to aid gastric emptying during nasogastric feeding. Intracranial pressure increased to 39mmHg from a baseline of 15-20mmHg. The same dose of metoclopramide was repeated the next day during transcranial doppler studies with an increase in ICP to 34mmHg and an associated rise in middle cerebral artery systolic blood velocity from 122cms-1 to 150cms-1. This effect of metoclopramide has not been previously reported. |
| | |
Authors:
|
Simon Deehan; Geoffrey J Dobb |
Related Documents
:
|
3111189 - Self-retaining brain retractor pressure during intracranial procedures. 2871509 - Evaluation of icp by computerized bedside monitoring: methods and clinical significance. 18329049 - Cerebral perfusion pressure in giraffe: modelling the effects of head-raising and -lowe... 21181379 - Assessment of left atrial function in diabetes mellitus by left atrial volume tracking ... 17019549 - Transfusion of erythrocyte concentrates produces a variable increment on cerebral oxyge... 9416299 - Hypertonic/hyperoncotic saline reliably reduces icp in severely head-injured patients w... 2498449 - Carbon dioxide mandatory ventilation (co2mv): a new method for weaning from mechanical ... 8864769 - Effect of noise stress on some cardiovascular parameters and audiovisual reaction time. 606739 - Accumulation of technetium-99m stannous pyrophosphate in contused myocardium. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of neurosurgical anesthesiology Volume: 14 ISSN: 0898-4921 ISO Abbreviation: J Neurosurg Anesthesiol Publication Date: 2002 Apr |
Date Detail:
|
Created Date: 2002-03-21 Completed Date: 2002-05-07 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8910749 Medline TA: J Neurosurg Anesthesiol Country: United States |
Other Details:
|
Languages: eng Pagination: 157-60 Citation Subset: IM |
Affiliation:
|
Intensive Care Unit, Royal Perth Hospital, Perth, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Accidents, Traffic Adult Antiemetics / adverse effects* Cerebrovascular Circulation / physiology Craniocerebral Trauma / physiopathology*, ultrasonography Glasgow Coma Scale Humans Intracranial Pressure / drug effects* Male Metoclopramide / adverse effects* Monitoring, Intraoperative Ultrasonography, Doppler, Transcranial |
| Chemical | |
Reg. No./Substance:
|
0/Antiemetics; 364-62-5/Metoclopramide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Should one rely on capnometry when a capnogram is not seen?
Next Document: Elimination of donor-specific alloreactivity prevents cytomegalovirus-accelerated chronic rejection ...