| Methylprednisolone therapy for short-term prevention of SUNCT syndrome. | |
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MedLine Citation:
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PMID: 19673911 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is characterized by severe and frequent daily pain attacks causing transient physical disability for the patients during the headache period. Currently there is no option for abortive treatment of the attacks, mainly due to the short-lived nature and frequency of the repeated headaches, while highly efficacious therapy is also unavailable for short-term prevention. We report rapidly suppressed headache attacks with orally administered methylprednisolone in eight headache periods of three patients with idiopathic, episodic SUNCT syndrome. The remission was maintained until the period was over in all cases. Although the mechanism of methylprednisolone action is unclear, it is probably based on the anti-inflammatory effects of the drug. |
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Authors:
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A Trauninger; B Alkonyi; N Kovács; S Komoly; Z Pfund |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-02-01 |
Journal Detail:
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Title: Cephalalgia : an international journal of headache Volume: 30 ISSN: 1468-2982 ISO Abbreviation: Cephalalgia Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-10-01 Completed Date: 2011-01-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200710 Medline TA: Cephalalgia Country: England |
Other Details:
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Languages: eng Pagination: 735-9 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Pécs, Hungary. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Humans Male Methylprednisolone / therapeutic use* Middle Aged Neuroprotective Agents / therapeutic use* SUNCT Syndrome / physiopathology, prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/Neuroprotective Agents; 83-43-2/Methylprednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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