Document Detail

Methylprednisolone pulse therapy in dermatomyositis.
MedLine Citation:
PMID:  6628798     Owner:  NLM     Status:  MEDLINE    
A high dose of methylprednisolone (pulse therapy) was given to 3 patients with uncontrolled dermatomyositis (DM) accompanied by severe muscle weakness. The effects of pulse therapy were compared with findings in 5 patients with severe DM who were treated with the usual dose of prednisolone (controls). The pulse therapy led to an improvement in the clinical symptoms in the 3 patients with uncontrolled DM, who were in danger of aspiration pneumonia. A rapid reduction in muscle enzyme levels in this group was also evident.
T Yanagisawa; M Sueishi; Y Nawata; T Akimoto; T Nozaki; T Koike; H Tomioka; A Kumagai
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Dermatologica     Volume:  167     ISSN:  0011-9075     ISO Abbreviation:  Dermatologica     Publication Date:  1983  
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0211607     Medline TA:  Dermatologica     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  47-51     Citation Subset:  IM    
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MeSH Terms
Creatine Kinase / blood
Dermatomyositis / drug therapy*
Injections, Intravenous
Methylprednisolone / administration & dosage,  therapeutic use*
Middle Aged
Reg. No./Substance:
83-43-2/Methylprednisolone; EC Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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