| Methylmercury and elemental mercury differentially associate with blood pressure among dental professionals. | |
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MedLine Citation:
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PMID: 22494934 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Methylmercury-associated effects on the cardiovascular system have been documented though discrepancies exist, and most studied populations experience elevated methylmercury exposures. No paper has investigated the impact of low-level elemental (inorganic) mercury exposure on cardiovascular risk in humans. The purpose of this study was to increase understanding of the association between mercury exposure (methylmercury and elemental mercury) and blood pressure measures in a cohort of dental professionals that experience background exposures to both mercury forms. Dental professionals were recruited during the 2010 Michigan Dental Association Annual Convention. Mercury levels in hair and urine samples were analyzed as biomarkers of methylmercury and elemental mercury exposure, respectively. Blood pressure (systolic, diastolic) was measured using an automated device. Distribution of mercury in hair (mean, range: 0.45, 0.02-5.18μg/g) and urine (0.94, 0.03-5.54μg/L) correspond well with the US National Health and Nutrition Examination Survey. Linear regression models revealed significant associations between diastolic blood pressure (adjusted for blood pressure medication use) and hair mercury (n=262, p=0.02). Urine mercury results opposed hair mercury in many ways. Notably, elemental mercury exposure was associated with a significant systolic blood pressure decrease (n=262, p=0.04) that was driven by the male population. Associations between blood pressure and two forms of mercury were found at exposure levels relevant to the general population, and associations varied according to type of mercury exposure and gender. |
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Authors:
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Jaclyn M Goodrich; Yi Wang; Brenda Gillespie; Robert Werner; Alfred Franzblau; Niladri Basu |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-9 |
Journal Detail:
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Title: International journal of hygiene and environmental health Volume: - ISSN: 1618-131X ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100898843 Medline TA: Int J Hyg Environ Health Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier GmbH. All rights reserved. |
Affiliation:
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Department of Environmental Health Sciences, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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