Document Detail

Methylene blue encephalopathy: a case report and review of published cases.
MedLine Citation:
PMID:  23923673     Owner:  NLM     Status:  In-Process    
Methylene blue is a cationic thiazine dye useful in staining parathyroid glands during surgical resection. There have been a number of reports of altered neurologic status postoperatively in patients who are taking antidepressant medications when they received methylene blue for their surgery. We present a case report and review 30 additional cases that have been reported in the literature. It has been suggested that in susceptible individuals an interaction occurs between methylene blue and serotonergic agents that precipitates serotonin syndrome. Because people with hyperparathyroidism commonly experience depression as part of their illness, anesthesia practitioners should exercise increased vigilance when administering methylene blue to these patients.
Ellen Shopes; Wayne Gerard; Jessica Baughman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  AANA journal     Volume:  81     ISSN:  0094-6354     ISO Abbreviation:  AANA J     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-08-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0431420     Medline TA:  AANA J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  215-21     Citation Subset:  N    
Tucson Veterans Affairs (VA) Health Care System, Tucson, Arizona, USA.
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