Document Detail

Methyl green is a substitute for distamycin A in the formation of distamycin A/DAPI C-bands.
MedLine Citation:
PMID:  6654329     Owner:  NLM     Status:  MEDLINE    
The DA/DAPI technique has been found to be useful in the identification of specific chromosomal regions on human chromosomes. The realization that distamycin A (DA) is no longer commercially available has necessitated the development of an alternative technique. We describe a technique, MG/DAPI, which substitutes the AT-specific dye methyl green for distamycin A and gives results identical to those of the DA/DAPI technique.
T A Donlon; R E Magenis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human genetics     Volume:  65     ISSN:  0340-6717     ISO Abbreviation:  Hum. Genet.     Publication Date:  1983  
Date Detail:
Created Date:  1984-02-15     Completed Date:  1984-02-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613873     Medline TA:  Hum Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  144-6     Citation Subset:  IM    
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MeSH Terms
Chromosome Banding / methods*
DNA / genetics
Heterochromatin / ultrastructure
Methyl Green*
Rosaniline Dyes*
Reg. No./Substance:
0/Distamycins; 0/Heterochromatin; 0/Pyrroles; 0/Rosaniline Dyes; 636-47-5/stallimycin; 82-94-0/Methyl Green; 9007-49-2/DNA

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