Document Detail

Methotrexate therapy of tubal pregnancy.
MedLine Citation:
PMID:  7686179     Owner:  NLM     Status:  MEDLINE    
Reports of successful treatment of ectopic pregnancies by administration of methotrexate have recently attracted a great deal of attention. This review summarizes the results of therapy with methotrexate in tubal pregnancy. Different technical approaches and pharmacological doses have been reported. These methods, however, present various problems, including the occurrence of toxicity, long therapeutic periods and treatment failure. With proper selection of patients, a success rate of approximately 90% has been achieved. Preliminary assessment of subsequent fertility provides promising results. However, the majority of the reports do not include controls.
M Goldenberg; D Bider; D Admon; S Mashiach; G Oelsner
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  8     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-07-23     Completed Date:  1993-07-23     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  660-6     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
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MeSH Terms
Chorionic Gonadotropin / blood
Chorionic Gonadotropin, beta Subunit, Human
Heart Rate, Fetal
Methotrexate / adverse effects,  therapeutic use*
Peptide Fragments / blood
Pregnancy, Tubal / diagnosis,  drug therapy*
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Peptide Fragments; 59-05-2/Methotrexate

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