Document Detail

Methotrexate infusions in poor prognosis acute lymphoblastic leukemia: II. High-dose methotrexate (HDM) in acute lymphoblastic leukemia in childhood: a pilot study from April 1981.
MedLine Citation:
PMID:  3462466     Owner:  NLM     Status:  MEDLINE    
The pilot study using HDM in all cases of ALL in childhood had been run for 4 1/2 years as of September 1985. Fourteen (23%) of all 62 diagnosed cases of ALL had WBC above 50 X 10(9)/L, all 14 achieved CR. Three of them were below one year of age, two also had WBC above 400 X 10(9)/L, the third infant had B-cell-leukemia. The remaining 11 children received our new HDM protocol (Fig. 1), one of them had relapsed (BM) as of September 1985.
P J Moe; F Wesenberg; S Kolmannskog
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical and pediatric oncology     Volume:  14     ISSN:  0098-1532     ISO Abbreviation:  Med. Pediatr. Oncol.     Publication Date:  1986  
Date Detail:
Created Date:  1986-10-07     Completed Date:  1986-10-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7506654     Medline TA:  Med Pediatr Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  189-90     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Infant, Newborn
Leukemia, Lymphoid / drug therapy*
Methotrexate / therapeutic use*
Pilot Projects
Time Factors
Reg. No./Substance:

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