Document Detail


Methotrexate-based bilateral uterine arterial chemoembolization for treatment of cesarean scar pregnancy.
MedLine Citation:
PMID:  20726832     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have evaluated the efficacy of methotrexate-based bilateral uterine arterial chemoembolization for treating cesarean scar pregnancy (CSP) in 52 women between January 2005 and December 2009. Ten patients experienced massive vaginal hemorrhage after a misdiagnosis and subsequent curettage. Bleeding in these patients was reduced after chemoembolization. Dilation and curettage was not done in five of these patients because ultrasound scanning showed sparse or no blood flow in the previous gestational sac area. The five remaining patients, along with additional 42 patients who were diagnosed with CSP, underwent ultrasound-guided dilation and curettage within 24-48 hours following chemoembolization. Patients tolerated the procedure well and only mild bleeding occurred. The positive clinical outcomes in these patients support the use of bilateral uterine artery chemoembolization for the treatment of CSP.
Authors:
Fengbing Liang; Jing He
Publication Detail:
Type:  Journal Article     Date:  2010-08-23
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  89     ISSN:  1600-0412     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-18     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  England    
Other Details:
Languages:  eng     Pagination:  1592-4     Citation Subset:  IM    
Affiliation:
Obstetrics Department, Women's Hospital, School of Medicine, Zhejiang University, Zhejiang, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cesarean Section / adverse effects*,  methods
Cicatrix / etiology,  therapy*
Cohort Studies
Dilatation and Curettage
Embolization, Therapeutic / methods*
Female
Follow-Up Studies
Gestational Age
Humans
Methotrexate / administration & dosage*
Pregnancy
Pregnancy, Ectopic / prevention & control
Retrospective Studies
Risk Assessment
Treatment Outcome
Uterine Artery / drug effects*
Uterine Rupture / prevention & control
Chemical
Reg. No./Substance:
59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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