| Methods for the assessment of small-bowel and colonic transit. | |
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MedLine Citation:
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PMID: 22293166 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Transit assessment of the small intestine and colon is relevant in the study of physiology, pathophysiology, and pharmacodynamics, and there is increasing use of small-bowel and colonic transit measurements in clinical practice as well. The main methods that are applied in clinical practice are substrate-hydrogen breath tests for small-bowel transit and radiopaque markers for colonic transit. Over the past 2-3 decades, scintigraphy has become the preferred standard in research studies, particularly for studies of pathophysiology and pharmacodynamics. New approaches include experimental stable isotope measurement of orocecal transit and the recently approved method using a wireless motility capsule that is validated as an accurate measurement of small-bowel and colonic transit. |
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Authors:
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Lawrence A Szarka; Michael Camilleri |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Seminars in nuclear medicine Volume: 42 ISSN: 1558-4623 ISO Abbreviation: Semin Nucl Med Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-02-01 Completed Date: 2012-08-23 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 1264464 Medline TA: Semin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 113-23 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Breath Tests Colon / physiology* Diagnostic Imaging Diagnostic Techniques and Procedures* / instrumentation Gastrointestinal Transit* Humans Intestine, Small / physiology* |
| Grant Support | |
ID/Acronym/Agency:
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R01 DK067071-08/DK/NIDDK NIH HHS; R01 DK079866-01A2/DK/NIDDK NIH HHS; R01-DK-079866/DK/NIDDK NIH HHS; R01-DK-1RC1-DK086182/DK/NIDDK NIH HHS; R01-DK-67071/DK/NIDDK NIH HHS; RC1 DK086182-02/DK/NIDDK NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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