Document Detail

Methodology and results of intravenous thrombolysis in acute myocardial infarction.
MedLine Citation:
PMID:  3100039     Owner:  NLM     Status:  MEDLINE    
For the vast majority of patients with acute myocardial infarction, intravenous thrombolysis is at present the only therapeutic approach aimed at early reperfusion of the ischemic myocardium. Rapid recanalization of the infarct-related coronary artery is achieved in at least 50-60% of the patients by short-term high-dose infusions of streptokinase or urokinase with a low risk of bleeding. A substantial reduction of infarct size, however, can be expected in only a minority of patients, mostly in those who are treated very early. The effects of intravenous thrombolysis on early and late mortality from acute myocardial infarction are still equivocal; more conclusive data may be expected from ongoing randomized trials.
K L Neuhaus
Related Documents :
7315719 - Intracoronary thrombolysis in acute myocardial infarction: experimental background and ...
17172929 - Coronary blood flow in patients with cardiac syndrome x.
15261609 - Cerebral amyloid angiopathy and thrombolysis-related intracerebral haemorrhage.
2421439 - Intracoronary thrombolysis and early bypass surgery for acute myocardial infarct: five ...
9507439 - Fast-tracking of myocardial infarction by paramedics.
6751059 - Streptokinase in acute myocardial infarction: western washington randomized trial--prot...
2299079 - Transthoracic two-dimensional high frequency (7.5 mhz) ultrasonic visualization of the ...
12417269 - Mechanisms of plaque stabilization for the dihydropyridine calcium channel blocker amlo...
23565859 - Duration of migraine is associated with cardiac diastolic dysfunction.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular and interventional radiology     Volume:  9     ISSN:  0174-1551     ISO Abbreviation:  Cardiovasc Intervent Radiol     Publication Date:  1986  
Date Detail:
Created Date:  1987-03-12     Completed Date:  1987-03-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8003538     Medline TA:  Cardiovasc Intervent Radiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  253-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Infusions, Intravenous
Myocardial Infarction / drug therapy*,  mortality
Streptokinase / administration & dosage*
Urokinase-Type Plasminogen Activator / administration & dosage
Reg. No./Substance:
EC 3.4.-/Streptokinase; EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Streptokinase, urokinase, and tissue plasminogen activator: pharmacokinetics, relative advantages, a...
Next Document:  Early diagnosis and medical treatment of the persistent ductus arteriosus in infants.