| Methodology and reporting of systematic reviews and meta-analyses of observational studies in psychiatric epidemiology: systematic review. | |
MedLine Citation:
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PMID: 22661677 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Relatively little is known of the use of systematic review and synthesis methods of non-randomised psychiatric epidemiological studies, which play a vital role in aetiological research, planning and policy-making. AIMS: To evaluate reviews of psychiatric epidemiological studies of functional mental disorders that employed synthesis methods such as systematic review or meta-analysis, or other forms of quantitative review. METHOD: We searched the literature to identify appropriate reviews published during the period 1996 to April 2009. Selected reviews were evaluated using published review guidelines. RESULTS: We found 106 reviews in total, of which 38 (36%) did not mention method of data abstraction from primary studies at all. Many failed to mention study quality, publication bias, bias and confounding. In 73 studies that performed a meta-analysis, 58 (79%) tested for heterogeneity and of these, 47 found significant heterogeneity. Studies that detected heterogeneity made some allowance for this. A major obstacle facing reviewers is the wide variation between primary studies in the use of instruments to measure outcomes and in sampling methods used. CONCLUSIONS: Many deficiencies found in systematic reviews are potentially remediable, although synthesis of primary study findings in a field characterised by so many sources of heterogeneity will remain challenging. |
Authors:
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Traolach S Brugha; Ruth Matthews; Zoe Morgan; Trevor Hill; Jordi Alonso; David R Jones |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: The British journal of psychiatry : the journal of mental science Volume: 200 ISSN: 1472-1465 ISO Abbreviation: Br J Psychiatry Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-06-04 Completed Date: 2012-08-22 Revised Date: 2013-02-14 |
Medline Journal Info:
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Nlm Unique ID: 0342367 Medline TA: Br J Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 446-53 Citation Subset: IM |
Affiliation:
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Division of Psychiatry, Department of Health Sciences, University of Leicester, UK. tsb@leicester.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Epidemiologic Methods Humans Mental Disorders / epidemiology* Meta-Analysis as Topic* Publication Bias Review Literature as Topic* |
| Comments/Corrections | |
Comment In:
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Br J Psychiatry. 2012 Sep;201(3):248
[PMID:
22945928
]
Br J Psychiatry. 2013 Jan;202(1):75-6 [PMID: 23284154 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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