Document Detail

Methodology for quantifying absolute myocardial perfusion with PET and SPECT.
MedLine Citation:
PMID:  17430679     Owner:  NLM     Status:  MEDLINE    
Noninvasive quantitative measurement of myocardial perfusion has played an important role in cardiac research and also has potential applications in clinical imaging. Positron emission tomography (PET) methods for measuring absolute perfusion are well established, although the need for an on-site cyclotron has restricted its use to a limited number of centers. Single-photon emission CT (SPECT) also has potential for quantifying myocardial perfusion and has more widespread availability. In this article we review the basic principles of absolute myocardial perfusion quantification and the radiopharmaceuticals that are available for both PET and SPECT. We also examine the extent to which recent developments in instrumentation have increased the practicality of absolute perfusion quantification in PET and the potential for absolute quantification in SPECT.
Martin A Lodge; Frank M Bengel
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current cardiology reports     Volume:  9     ISSN:  1523-3782     ISO Abbreviation:  Curr Cardiol Rep     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-13     Completed Date:  2007-07-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100888969     Medline TA:  Curr Cardiol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  121-8     Citation Subset:  IM    
Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
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MeSH Terms
Artificial Intelligence
Coronary Artery Disease / pathology,  radionuclide imaging*
Myocardial Reperfusion / methods*
Positron-Emission Tomography / instrumentation,  methods*
Radiopharmaceuticals / diagnostic use
Tomography, Emission-Computed, Single-Photon / instrumentation,  methods*
Reg. No./Substance:

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