Document Detail


Methodology and analytic techniques used in clinical research: associations with journal impact factor.
MedLine Citation:
PMID:  19888048     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To describe research methodology and statistical reporting of published articles in high-impact-factor general medical journals compared with moderate-impact-factor obstetrics and gynecology journals.
METHODS: A cross-sectional analysis was performed on 371 articles published from January to June 2006 in six journals (high-impact-factor group: Journal of the American Medical Association, The Lancet, the New England Journal of Medicine; moderate-impact-factor group-American Journal of Obstetrics & Gynecology, British Journal of Obstetrics and Gynaecology, and Obstetrics & Gynecology). Articles were classified by level of evidence. Data abstracted from each article included number of authors, clearly stated hypothesis, sample size/power calculations, statistical measures, and use of regression analysis. Univariable analyses were performed to evaluate differences between the high-impact-factor and moderate-impact-factor groups.
RESULTS: The majority of published reports were observational studies (50%), followed by randomized controlled trials ([RCTs] 24%), case reports (14%), systematic reviews (6%), case series (1%), and other study types (4%). Within the high-impact-factor group, 35% were RCTs compared with 12% in the moderate-impact-factor group (relative risk 2.9, 95% confidence interval 1.9-4.4). Recommended statistical reporting (eg, point estimates with measures of precision) was more common in the high-impact-factor group (P<.005).
CONCLUSION: The proportion of RCTs published among the high-impact-factor group was three times that of the moderate group. Efforts to provide the highest level of evidence and statistical reporting have the potential to improve the quality of reports in the medical literature available for clinical decision making.
LEVEL OF EVIDENCE: III.
Authors:
Lindsay M Kuroki; Jenifer E Allsworth; Jeffrey F Peipert
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  114     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-11-05     Completed Date:  2009-12-02     Revised Date:  2013-12-16    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  877-84     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Gynecology
Humans
Journal Impact Factor*
Obstetrics
Randomized Controlled Trials as Topic
Research Design*
Grant Support
ID/Acronym/Agency:
K12RR023249/RR/NCRR NIH HHS; K24 HD001298/HD/NICHD NIH HHS; K24 HD001298-09/HD/NICHD NIH HHS; K24 HD01298/HD/NICHD NIH HHS; KL2RR024994/RR/NCRR NIH HHS; UL1 RR024992/RR/NCRR NIH HHS; UL1RR024992/RR/NCRR NIH HHS
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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