| Methodologies for the detection of adverse drug reactions: comparison of hospital databases, chart review and spontaneous reporting. | |
| | |
MedLine Citation:
|
PMID: 23027707 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
PURPOSE: To evaluate a methodology for adverse drug reactions (ADRs) detection through hospital databases. METHODS: A retrospective analysis was conducted to identify ADRs using diagnostic codes from databases, later validated by chart review. An independent chart review was performed for comparison, as well as assessment of spontaneous reports. RESULTS: 325 ADRs were identified (prevalence of 2.41%, positive predictive value of 87.6%). Independent chart review identified 9% of ADRs at a cost of 35 person-hours (versus two person-hours in databases). There were seven spontaneous reports of ADRs. CONCLUSIONS: Although not frequently used, the detection of ADRs through databases is a relatively less expensive, fast and effective methodology that can improve current pharmacovigilance systems. Copyright © 2012 John Wiley & Sons, Ltd. |
| | |
Authors:
|
Ana Miguel; Luís Filipe Azevedo; Fernando Lopes; Alberto Freitas; Altamiro Costa Pereira |
Related Documents
:
|
21354007 - Calcaneal intraosseous lipoma: a case report and review of the literature. 23689037 - Anaplastic ganglioglioma in the spinal cord: case report and literature review. 23352797 - Congenital parotid ectopia in accessory maxilla and facial cleft anomalies: three cases... 23476797 - Acquired melanonychia in chilean patients with essential thrombocythemia treated with h... 8699497 - Auto-erotic asphyxiation: three case reports. 10690997 - Bilateral focal motor status epilepticus with retained consciousness after stroke. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-10-1 |
Journal Detail:
|
Title: Pharmacoepidemiology and drug safety Volume: - ISSN: 1099-1557 ISO Abbreviation: Pharmacoepidemiol Drug Saf Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-10-2 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9208369 Medline TA: Pharmacoepidemiol Drug Saf Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 John Wiley & Sons, Ltd. |
Affiliation:
|
Centre for Research in Health Technologies and Information Systems (CINTESIS), Faculty of Medicine, Oporto University, Oporto, Portugal; Department of Ophthalmology, Hospital University Centre of Coimbra, Coimbra, Portugal. myworld_ana@hotmail.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cytokinesis in trypanosomes.
Next Document: Apolipoprotein A-I: Insights from redox proteomics for its role in neurodegeneration.