Document Detail


Methodologies for assessing exposures to metals: human host factors.
MedLine Citation:
PMID:  12915144     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Many factors affect bioavailability of metals. Host factors can be defined as any attribute that can influence the amount and degree of metal exposure. In this series of articles, a wide range of aspects are discussed concerning the methodologies for assessing exposures to metals. These aspects include speciation, bioaccessibility, and bioavailability in the environment, in food, and in feed. This article complements the articles by Peakall and Burger and by Calderón et al., reviewing human host factors. In this article, measurement and assessment methods are discussed as they apply to risk assessment, with examples for arsenic, cadmium, chromium, and lead, as well as special consideration for source issues and children's risk. Finally, several examples from the current literature are cited to illustrate some of the approaches presently in use as well as areas of research that require further consideration, including longitudinal studies, as well as better biomonitoring and assessment strategies.
Authors:
Mark Robson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Ecotoxicology and environmental safety     Volume:  56     ISSN:  0147-6513     ISO Abbreviation:  Ecotoxicol. Environ. Saf.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-13     Completed Date:  2003-12-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7805381     Medline TA:  Ecotoxicol Environ Saf     Country:  United States    
Other Details:
Languages:  eng     Pagination:  104-9     Citation Subset:  IM    
Affiliation:
School of Public Health, University of Medicine and Dentistry of New Jersey, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA. robson@eohsi.rutgers.edu
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MeSH Terms
Descriptor/Qualifier:
Animal Feed*
Animals
Biological Availability
Environmental Exposure*
Food Contamination*
Humans
Metals, Heavy / analysis,  pharmacokinetics,  toxicity*
Risk Assessment
Chemical
Reg. No./Substance:
0/Metals, Heavy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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